Fig. 1: Study design and filters for UKBB, FHS and ADNI cohorts. | Translational Psychiatry

Fig. 1: Study design and filters for UKBB, FHS and ADNI cohorts.

From: The impact of increasing levels of blood C-reactive protein on the inflammatory loci SPI1 and CD33 in Alzheimer’s disease

Fig. 1

The following three human datasets were analyzed in this study. UKBB: 279,176 participants (mean age 60.1 ± 5.5 years) of which baseline CRP was measured, and 803 incident AD cases were identified after 8.3 ± 0.9 years of follow-up. FHS: 3009 participants (mean age 60.8 ± 9.4 years) of which baseline CRP was measured (i.e., Exam 7), and 156 incident AD cases were identified after 14.9 ± 4.0 years of follow-up. ADNI: 321 MCI patients (mean age 75.0 ± 7.0 years) of which baseline CRP was measured, and 105 MCI-to-AD converters were identified after 31.8 ± 11.2 months of follow-up.

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