Table 1 Socio-demographic and clinical variables (n = 181).
Variables | Controls | Patients | Siblings | p |
---|---|---|---|---|
(n = 78) | (n = 78) | (n = 25) | ||
Male, n (%)d | 54 (69.2) | 54 (69.2) | 8 (32.0) | 0.002a,b |
Age, mean (SD)e | 30.3 (11.9) | 30.1 (12.3) | 29.8 (8.7) | 0.881 |
Body mass index (kg/m2), mean (SD)e | 26.5 (5.8) | 24.0 (4.5) | 25.8 (5.2) | 0.035c |
Tobacco smoking (yes), n (%)f | 8 (10.3) | 30 (38.5) | 5 (20.0) | <0.001c |
Lifetime psychoactive substance use (yes), n (%)f | 16 (20.5) | 49 (62.8) | 5 (20.0) | <0.001a,c |
Childhood trauma questionnaire (total score)e | 38.2 (13.2) | 40.7 (14.2) | 41.2 (13.9) | <0.001b,c |
Psychosis age of onset, mean (SD) | - | 28.4 (12.2) | - | - |
DUP (weeks), median (min-max) | - | 20.5 (0–1292) | - | - |
Pharmacological treatment (weeks), median (min-max) | - | 13.0 (0–155) | - | - |
Duration of psychosis (weeks), median (min-max) | - | 53 (4–1394) | - | - |
BPRS, mean (SD)e | 0.45 (1.43) | 8.41 (6.44) | 0.72 (1.46) | <0.001a,c |
Pharmacological treatment | ||||
Antipsychotics (AP) | - | 50 (64.1) | - | - |
Antidepressants (AD) | 1 (1.3) | |||
AP + AD | - | 10 (12.8) | - | - |
AP + Mood Stabilisers (MS) | - | 6 (7.7) | - | - |
AP + AD + MS | - | 3 (3.8) | - | - |
None | - | 8 (10.3) | - | - |