Fig. 3: Gamma-band auditory steady-state response (ASSR) related resting-state functional connectivity (rsFC) with left medial prefrontal cortex (MPFC) or left precentral gyrus (PrG) seeds and the mediation analysis model.
From: Cortical connectomic mediations on gamma band synchronization in schizophrenia
A Left MPFC-seeded rsFC with right STG, left postcentral gyrus (PoG), and right inferior frontal gyrus (IFG) significantly predicted 40 Hz ASSR in combined groups and within each group. B Left PrG-seeded rsFC at left supramarginal gyrus (SMG), left IFG, right PoG, left middle temporal gyrus (MTG), and left MPFC significantly predicted larger 40 Hz ASSR. Left is shown on the left side of the MRI image. C The significant effects of diagnosis (i.e., the differences of 40 Hz ASSR between the two diagnostic groups) on 40 Hz ASSR (path c) were nearly fully mediated by the top three rsFC (path c’ not significant). STG superior temporal gyrus, MPFC left medial prefrontal cortex, PoG postcentral gyrus, PrG precentral gyrus, SMG supramarginal gyrus, IFG inferior frontal gyrus, SZ patients with schizophrenia, HC healthy controls. Seed region was written in italic. *p < 0.05.
