Table 1 Demographics for patients and healthy controls.
ECT (n = 20) | TAU (n = 20) | Controls (n = 20) | P value | |||||
|---|---|---|---|---|---|---|---|---|
Age (years) | 44.9 ± 12 | 44.2 ± 15 | 43.6 ± 14 | 0.96 | ||||
Sex n (female) | 8 | 14 | 8 | 0.09 | ||||
Handedness n (right, left, ambidextrous) | 15, 2, 3 | 17, 2, 1 | 17, 2, 1 | 0.78 | ||||
BDI-II (Baseline) | 30.6 ± 8.1 | 26.8 ± 8.8 | 1.5 ± 2.4 | 0.17 | ||||
HAMD-21 (Baseline) | 21.4 ± 5.3 | 22.6 ± 5.1 | 0.65 ± 1.0 | 0.49 | ||||
Duration of episode (months) | 19.8 ± 17 | 8.2 ± 8 | n.a. | 0.01 | ||||
Number of episodes | 5.2 ± 4 | 2.7 ± 2 | n.a. | 0.03 | ||||
Time between scans (days) | 52.6 ± 24 | 67.3 ± 29 | 61.2 ± 17 | 0.16 | ||||
BDI-II (Follow up) | 20.8 ± 10.3 | 13.1 ± 8.4 | 1 ± 1.8 | 0.02 | ||||
HAMD-21 (Follow up) | 10.9 ± 8.1 | 5.6 ± 3.2 | 0.25 ± 0.8 | 0.01 | ||||
n (remitter1) | 9 | 15 | n.a. | 0.053 | ||||
n (responder or remitter2) | 11 | 20 | n.a. | 0.001 | ||||
n (non-responder) | 9 | 0 | n.a. | 0.001 | ||||
Medication | T1 | T2 | T1 | T2 | T1 | T2 | T1 | T2 |
SSRI (%) | 20 | 15 | 25 | 25 | 0 | 0 | 0.71 | 0.43 |
Dual antidepressants (%) | 55 | 50 | 35 | 40 | 0 | 0 | 0.20 | 0.53 |
Tricyclic antidepressants (%) | 15 | 20 | 25 | 30 | 0 | 0 | 0.43 | 0.47 |
Tranylcypromine (%) | 5 | 10 | 0 | 0 | 0 | 0 | 0.31 | 0.15 |
Moclobemide (%) | 5 | 5 | 0 | 0 | 0 | 0 | 0.31 | 0.31 |
No antidepressant (%) | 10 | 5 | 20 | 5 | 100 | 100 | 0.38 | 0.39 |
Lithium (%) | 35 | 30 | 15 | 20 | 0 | 0 | 0.14 | 0.47 |
