Fig. 1: Increased oxidative stress and microglia activation in the low protein induced IUGR offspring at P35. | Translational Psychiatry

Fig. 1: Increased oxidative stress and microglia activation in the low protein induced IUGR offspring at P35.

From: Low protein-induced intrauterine growth restriction as a risk factor for schizophrenia phenotype in a rat model: assessing the role of oxidative stress and neuroinflammation interaction

Fig. 1

Images for 8-oxo-dG (label for mitochondrial DNA oxidation), Iba-1 (label for microglia) and CD68 (label for activated microglia) in both control (n = 5) and IUGR (n = 7) groups. IUGR leads to significant increase in 8-oxo-dG intensity (a.u.), Iba-1 intensity (a.u.) and Iba-1 cell count, as well as CD68 cell count in the ACC as compared to controls. Results are mean ± STD, *p = 0.05, **p < 0.01, ****p < 0.0001 Control vs IUGR. Scale bar: 60 μm.

Back to article page