Table 5 Descriptive analyses of the three clusters.

From: Medication adherence and cognitive performance in schizophrenia-spectrum and bipolar disorder: results from the PsyCourse Study

 

Cluster 1 (n = 279)

Cluster 2 (n = 336)

Cluster 3 (n = 247)

Statistics

p value

Post hoc analysis

Mean (SD) or n (%)

Mean (SD) or n (%)

Mean (SD) or n (%)

Illness duration, y

13.37 (10.95)

11.75 (9.78)

11.61 (9.30)

F(2, 812) = 2.54

<0.08

 

Diagnosis

   

X2(2) = 48.53

<0.001*

 

Schizophrenia-spectrum disorder

184 (42.0)

167 (38.0)

88 (20.0)

  

1 > 3

Bipolar disorder

95 (22.5)

169 (39.9)

159 (37.6)

  

1 < 3

Premorbid IQ

25.70 (5.44)

28.30 (4.33)

30.20 (3.92)

F(2, 756) = 55.64

<0.001*

1 < 2, 1 < 3, 2 < 3

Adherence Scale

1.78 (1.42)

1.82 (1.37)

1.68 (1.15)

F(2, 859) = 0.81

0.444

 

No. of medications

2.70 (1.36)

2.54 (1.34)

2.30 (1.08)

F(2, 859) = 6.22

0.002*

1 > 3

GAF score

52.62 (12.54)

58.60 (13.45)

61.35 (13.16)

F(2, 859) = 31.73

<0.001*

1 < 2, 1 < 3

CGI score

4.41 (0.90)

3.99 (1.03)

3.73 (0.99)

F(2, 856) = 32.73

<0.001*

1 > 2, 1 > 3

PANSS

      

PANSS positive sum score

13.10 (5.50)

10.85 (4.46)

9.61 (3.87)

F(2, 853) = 38.05

<0.001*

1 > 2, 1 > 3, 2 > 3

PANSS negative sum score

14.73 (6.46)

12.04 (5.71)

10.65 (4.21)

F(2, 844) = 36.23

<0.001*

1 > 2, 1 > 3, 2 > 3

PANSS general sum score

28.55 (8.57)

25.10 (7.73)

23.15 (6.61)

F(2, 831) = 32.30

<0.001*

1 > 2, 1 > 3

PANSS total sum score

56.66 (17.77)

48.03 (15.60)

43.34 (12.66)

F(2, 816) = 47.38

<0.001*

1 > 2, 1 > 3, 2 > 3

IDS-C30 sum score

14.01 (10.85)

12.93 (10.54)

11.93 (10.05)

F(2, 771) = 2.34

0.097

 

YMRS sum score

3.61 (5.22)

3.01 (4.94)

2.72 (4.70)

F(2, 838) = 2.18

0.113

 
  1. z-scores were adjusted for age and sex for cluster analysis.
  2. CGI Clinical Global Impression, GAF Global Assessment of Functioning, IDS-C30 Inventory of Depressive Symptomatology, clinician rated, PANSS Positive and Negative Syndrome Scale, SD Standard deviation, y years, YMRS Young Mania Rating Scale.
  3. *p < 0.003 significant (Bonferroni corrected for multiple testing).