Fig. 1: Experimental Design. | Translational Psychiatry

Fig. 1: Experimental Design.

From: Mu-opioid receptor-expressing neurons in the paraventricular thalamus modulate chronic morphine-induced wake alterations

Fig. 1

A Amount consumed in drinking water in average mL per animal per day. B Spontaneous somatic withdrawal signs between morphine-treated mice and saccharin-treated mice. C Somatic withdrawal signs in mice that drank morphine precipitated by 1 mg/kg Naloxone or Saline. D Timeline of experiments. E Example schematic showing placement of electrodes 1 mm from bregma in each quadrant and on the nuchal muscles with example EEG and EMG traces. F Image of mouse with electrode cap. G Example traces of Wake, NREM, and REM in 4 s epochs.

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