Fig. 3: Screen of immediate early gene expression across brain regions. | Translational Psychiatry

Fig. 3: Screen of immediate early gene expression across brain regions.

From: Mu-opioid receptor-expressing neurons in the paraventricular thalamus modulate chronic morphine-induced wake alterations

Fig. 3

A Representative image of hippocampus from saline group. B Hippocampus from acute morphine group. C Chronic morphine hippocampus. D Representative image of PVT (paraventricular nucleus of the thalamus) from saline group. E PVT from acute morphine group. F Chronic morphine PVT. G Representative image of LH (lateral hypothalamus) from saline group. H LH from acute morphine group. I Chronic morphine LH. J Representative image of NAc (nucleus accumbens) from saline group. K NAc from acute morphine group. L Chronic morphine LH. M Quantification of cFOS expression in LH across morphine timepoints. N cFOS expression in PVT across morphine timepoints. O cFOS expression in NAc quantified across morphine timepoints. P Quantification of cFOS expression in VTA across morphine timepoints. Q cFOS expression levels in Dorsal Hippocampus across morphine timepoints. R cFOS expression in ventral hippocampus at control, acute, and chronic morphine. Images were taken at 10× quantification and scale bars represent 500 um.

Back to article page