Fig. 4: Three-cluster solution brain differences at term-equivalent age.

A Colored voxels indicate regions with significantly larger log-Jacobian determinant values in the resilient subgroup (subgroup 1) compared to the intermediate subgroup (subgroup 3) in i) left insula and the ii) bilateral orbitofrontal cortices (p < 0.05). GLM included sex and PMA at scan as covariates and TFCE and FWE corrections were applied. B Voxels showing significantly larger degree centrality values in the resilient subgroup (subgroup) 1 compared to the intermediate subgroup (subgroup 3) are seen in an overlapping left orbitofrontal region at p < 0.05. GLM included sex, PMA at scan and motion (standardized DVARS) as covariates; TFCE and FWE were applied. C Colored voxels represent white matter regions showing i) significantly higher FA values in the intermediate subgroup compared to the at-risk subgroup and ii) significantly higher MD values in the at-risk subgroup compared to the intermediate subgroup (p < 0.05). T-statistic values are represented in the color bar, where red colored voxels indicate smaller T-statistic values and yellow voxels indicate higher T-statistic values ranging between 1.70 and 5.50.