Fig. 1: Psilocybin reduces marble burying - Role of 5-HT2A and 5-HT1A receptors. | Translational Psychiatry

Fig. 1: Psilocybin reduces marble burying - Role of 5-HT2A and 5-HT1A receptors.

From: Effect of psilocybin on marble burying in ICR mice: role of 5-HT1A receptors and implications for the treatment of obsessive-compulsive disorder

Fig. 1

Effect of psilocybin 4.4 mg/kg, escitalopram 5 mg/kg, M100907 2 mg/kg, and M100907 2 mg/kg + psilocybin 4.4 mg/kg, 8-OH-DPAT 2 mg/kg and 8-OH-DPAT 2 mg/kg + psilocybin 4.4 mg/kg on total marbles buried over 30 min. One-way ANOVA: F6,56 = 15.33 p < 0.0001. **p < 0.01 vs. VEH, #p < 0.01 vs. PSIL, n = 8–16 (Bonferroni’s multiple comparisons test).

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