Fig. 4: Summary two-step MR estimates derived from the IVW methods for the effect of inactivity on MDD. | Translational Psychiatry

Fig. 4: Summary two-step MR estimates derived from the IVW methods for the effect of inactivity on MDD.

From: Dissecting the causal association between social or physical inactivity and depression: a bidirectional two-sample Mendelian Randomization study

Fig. 4

‘A’ indicates two-step MR results of leisure/social inactivity on MDD. ‘B’ indicates two-step MR results of physical inactivity on MDD. BFP, body fat percentage; BMI, body mass index; CI, confidence interval; IVW, inverse variance weighted method; MDD, major depressive disorder; MR, Mendelian Randomization; Volume of GM in RHG, volume of grey matter in right heschl’s gyrus; Weighted-mean OD in LAR, weighted-mean orientation dispersion index in tract left acoustic radiation; Volume of RC, volume of right caudate; Area of LPG, area of precentral gyrus in the left hemisphere; Mean OD in RSS, mean orientation dispersion index in right sagittal stratum; Mean ISOVF in RSCR, mean isotropic or free water volume fraction in right superior corona radiata.

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