Fig. 5: Effect of PNS exposure on the expression of excitatory and inhibitory markers in the ventral hippocampus in male and female adolescent offspring.

The analyses of VGLUT1 and VGAT were performed as whole PNS group (panels A, C and E) or after the separation in vulnerable (PNS-vul) and resilient (PNS-res) to the gestational manipulation (B, D and F). The data shows mean ± SEM of n = 14 to 30 per group for panels A, C and E whereas of n = 5 to 19 per group for panels B, D and F. Statistical analysis (panels A, C, and E): two-way ANOVA, PNS effect, ****p < 0.0001, ***p < 0.001. Statistical analysis (panels B, D, and F): one-way ANOVA, Tukey’s post hoc, *p < 0.05, **p < 0.01, statistically different from the respective CT group.