Fig. 6: Effect of PNS exposure on the expression of glucocorticoid-related markers in the ventral hippocampus in male and female adolescent offspring.

The analysis of Nr3c1 (glucocorticoid receptor) and Sgk1 were performed as whole PNS group (panels A, C) or after the separation in vulnerable (PNS-vul) and resilient (PNS-res) to the gestational manipulation (panels B, D). The data shows mean ± SEM of n = 14 to 30 per group for panels (A) and (C) whereas of n = 5 to 19 per group for panels (B) and (D). Statistical analysis: two-way ANOVA, PNS effect, **p < 0.01; Tukey’s post hoc, *p < 0.05, statistically different from CT male. Statistical analysis (panels B, D): one-way ANOVA, Tukey’s post hoc, **p < 0.01, statistically different from CT male, #p < 0.05, statistically different from CT and PNS-res male groups.