Fig. 5: Glial fibrillary acidic protein (GFAP) and Ionized calcium binding adaptor molecule 1 (Iba1) expression in the dentate gyrus. | Translational Psychiatry

Fig. 5: Glial fibrillary acidic protein (GFAP) and Ionized calcium binding adaptor molecule 1 (Iba1) expression in the dentate gyrus.

From: Electroconvulsive therapy is associated with increased immunoreactivity of neuroplasticity markers in the hippocampus of depressed patients

Fig. 5

The photomicrographs show the expression in the granule cell layer (GCL), subgranular zone (SGZ) and cornu ammonis 4 (CA4) in a healthy control donor (HC; A), a control donor with a depressive disorder (DC; B), and a donor who received electroconvulsive therapy during life (ECT; C). The distribution of the groups is shown in percentages of cell area occupied (%AO) by GFAP or Iba1 in the GCL (D), SGZ (E), and CA4 (F). No differences in mean %AO by GFAP or Iba1 were found between the groups. Scale bar=50 µm.

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