Table 1 Individuals with ASD (n = 271) according to their KYN/TRP and 5-HT status.

From: Impact of IDO activation and alterations in the kynurenine pathway on hyperserotonemia, NAD+ production, and AhR activation in autism spectrum disorder

 

plasma KYN/TRP ≤ 5%

plasma KYN/TRP > 5%

Total

Whole-blood 5-HT ≤ 16 y/o: ≤830 nM > 16 y/o: ≤655 nM

16 (5.9%)

142 (52.4%)

158 (58.3%)

Whole-blood 5-HT ≤ 16 y/o: >830 nM > 16 y/o: >655 nM

96 (35.4%)

17 (6.3%)

113 (41.7%)

Total

112 (41.3%)

159 (58.7%)

271 (100%)

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