Table 3 Associations with ccf-mtDNA controlling for age, diabetes status, and antidepressant use.

Variable	Entire group		PTSD-		PTSD+
Variable	β	p value	β	p value	β	p value
BMI	−0.021	0.767	0	0.998	−0.008	0.941
HbA1c	0.203	0.006	0.21	0.029	0.285	0.084
Pre-dex cortisol (µg/ml)^a	−0.033	0.614	−0.06	0.511	0.011	0.91
Post-dex cortisol (µg/ml)^a	0.05	0.475	0.008	0.931	0.082	0.423
Pre-dex ACTH (pg/ml)^a	−0.116	0.097	−0.091	0.358	−0.113	0.28
Post-dex ACTH (pg/ml)^a	0.059	0.423	0.123	0.245	−0.005	0.962
ACTH decline (pg/ml)^a	−0.170	0.02	−0.143	0.168	−0.163	0.132
Cortisol decline (µg/ml)^a	−0.143	0.043	−0.18	0.069	−0.069	0.506
IC_50-DEX (nM)	0.142	0.038	0.135	0.159	0.099	0.329
Time since worst event (months)	−0.051	0.449	0.147	0.119	0.012	0.904
BDI2 score	−0.184	0.011	−0.195	0.039	−0.019	0.854
pcl score	−0.187	0.008	−0.177	0.055	0.019	0.847
CAPS total score (current)	−0.192	0.007	−0.238	0.009	−0.062	0.533
CAPS B (current)	−0.168	0.018	−0.117	0.21	−0.059	0.552
CAPS C (current)	−0.155	0.03	−0.118	0.197	0.033	0.742
CAPS D (current)	−0.226	0.001	−0.216	0.018	−0.141	0.155
CAPS total score (lifetime)	−0.194	0.007	−0.165	0.079	−0.075	0.453
Perceived Stress Scale	−0.118	0.094	−0.069	0.468	0.031	0.758

PTSD post-traumatic stress disorder, BMI body mass index, HbA1c hemoglobin A1c, ACTH adrenocorticotropic hormone, IC_50-DEX the concentration of dexamethasone at which 50% of lysozyme activity is inhibited, BDI2 Beck Depression Inventory 2, PCL PTSD Checklist, CAPS Clinician-Administered PTSD Scale.
^aStandardized values were used.

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