Table 1 Thalamocortical model parameter changes.

From: Neurophysiological evidence that frontoparietal connectivity and GABA-A receptor changes underpin the antidepressant response to ketamine

  

F(DF)

P uncorr

P FDR

Extrinsics

AMPA Forward

13.95(2,26)

1.4 × 10−5

1.4 × 10−3

AMPA Backward

0.94(2,26)

0.39

0.39

NMDA Forward

0.24(2,26)

0.24

0.32

NMDA Backward

0.16(2,26)

0.16

0.31

Intrinsics

Frontal SP to SP

1.73(2,26)

0.18

0.22

Frontal SI to SP

3.37(2,26)

0.04

0.16

Frontal RL to SS

2.35(2,26)

0.11

0.18

Frontal TP to RL

2.35(2,26)

0.11

0.18

Parietal SP to SP

2.87(2,26)

0.07

0.16

Parietal SI to SP

0.56(2,26)

0.57

0.57

Parietal RL to SS

0.59(2,26)

0.56

0.57

Parietal TP to RL

0.59(2,26)

0.56

0.57

Time constants

Frontal AMPA

1.86(2,26)

0.16

0.24

Frontal GABA

5.09(2,26)

0.009

0.050

Frontal NMDA

2.52(2,26)

0.09

0.18

Parietal AMPA

0.46(2,26)

0.63

0.75

Parietal GABA

0.12(2,26)

0.89

0.89

Parietal NMDA

4.10(2,26)

0.02

0.06