Table 2 Thalamocortical parameter changes in comparison dataset of healthy males without depression.

From: Neurophysiological evidence that frontoparietal connectivity and GABA-A receptor changes underpin the antidepressant response to ketamine

 

Parameter

F(DF)

P uncorr

P FDR

Extrinsics

AMPA Forward

23.18(2,23)

1.09 × 10−7

0.0000

AMPA Backward

3.15(2,23)

0.052

0.10

NMDA Forward

1.33(2,23)

0.27

0.36

NMDA Backward

0.74(2,23)

0.48

0.48

Intrinsics

Frontal SP to SP

12.77(2,23)

3.87 × 10−6

0.0003

Frontal SI to SP

10.48(2,23)

1.78 × 10−4

0.0007

Frontal RL to SS

4.32(2,23)

0.02

0.02

Frontal TP to RL

4.32(2,23)

0.02

0.02

Parietal SP to SP

4.43(2,23)

0.02

0.02

Parietal SI to SP

3.42(2,23)

0.04

0.04

Parietal RL to SS

4.93(2,23)

0.01

0.02

Parietal TP to RL

4.93(2,23)

0.01

0.02

Time constants

Frontal AMPA

17.63(2,23)

2.07 × 10−6

0.000

Frontal GABA

0.80(2,23)

0.46

0.48

Frontal NMDA

0.74(2,23)

0.48

0.48

Parietal AMPA

17.54(2,23)

2.18 × 10−6

0.000

Parietal GABA

0.75(2,23)

0.48

0.48

Parietal NMDA

3.35(2,23)

0.04

0.09