Fig. 2: SLCP treatment ameliorated social behavioral deficits in Tsc2+/− mice. | Translational Psychiatry

Fig. 2: SLCP treatment ameliorated social behavioral deficits in Tsc2+/− mice.

From: Amelioration of the brain structural connectivity is accompanied with changes of gut microbiota in a tuberous sclerosis complex mouse model

Fig. 2

a Three-chamber apparatus set-up of social behavioral preference test and the heatmaps of the representative mouse tracks from each group. b The time spent in the chambers of either the animal or the object was shown for each group. c The social preference indices between the object and the animal were shown. d Three-chamber apparatus set-up of social behavioral novelty test and the heatmaps of the representative mouse tracks from each group. e The time spent in the chambers of either the familiar animal or the stranger animal was shown for each group. f The social novelty indices between the familiar animal and the stranger animal were shown. WT (N = 9), Tsc2+/− (N = 8), and Tsc2+/−/SLCP (N = 8) mice were assessed. Data represent the mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, n.s. not significant. One-way ANOVA, post hoc Tukey’s test.

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