Fig. 6: Correlation plots of DTI metrics and bacterial taxa abundances. | Translational Psychiatry

Fig. 6: Correlation plots of DTI metrics and bacterial taxa abundances.

From: Amelioration of the brain structural connectivity is accompanied with changes of gut microbiota in a tuberous sclerosis complex mouse model

Fig. 6

a–f Scatter plots of the FA values of tracts between PFC and Amyg and the relative abundances of bacterial taxa in the phylum, class, and family with simple linear regression analysis. g–l Scatter plots of the AD values of tracts between PFC and Amyg and the relative abundances of bacterial taxa in the phylum, class, and family with simple linear regression analysis. m–p Scatter plots of the RD values of tracts between PFC and Amyg and the relative abundances of bacterial taxa in phylum, class, and family with simple linear regression analysis. q A circos plot shows the correlation between DTI metrics and the bacterial abundances at the genus level. The ribbon size represents the ranking of the r value in the correlation analyses. The color of each letter designated bacterial genus represents the positive (red) or negative (blue) correlation with the DTI metrics. WT (N = 9), Tsc2+/− (N = 8), and Tsc2+/−/SLCP (N = 8) mice were assessed. The correlation coefficient Spearman (r) was computed set at a 95% confidence interval; the p value represents two-tailed. Significance set at α = 0.05.

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