Table 1 Sample characteristics of first-episode psychosis (FEP) patients with clozapine use compared to those without.

From: Development of an individualized risk calculator of treatment resistance in patients with first-episode psychosis (TRipCal) using automated machine learning: a 12-year follow-up study with clozapine prescription as a proxy indicator

 

Clozapine Use

 

Characteristic

No, N = 1207a

Yes, N = 191a

T/\({\chi }^{2}\)

p-valueb

q-valuec

Age at first service contact

21.91 (3.41)

20.27 (3.30)

6.4

<0.001

<0.001

Sex

  

0.10

0.8

0.8

 Male

617 (51%)

100 (52%)

   

 Female

590 (49%)

91 (48%)

   

Years of education

10.82 (2.39)

10.14 (2.19)

3.9

<0.001

<0.001

Diagnosis

  

39

<0.001

<0.001

 Schizophrenia

775 (64%)

166 (87%)

   

 Other diagnoses of psychotic disorders

432 (36%)

25 (13%)

   

Age of illness onset

20.76 (3.47)

19.26 (3.38)

5.7

<0.001

<0.001

Treatment

  

3.8

0.052

0.072

 Early Intervention

616 (51%)

83 (43%)

   

 Standard Care

591 (49%)

108 (57%)

   

DUP days (log)

4.13 (1.87)

4.25 (1.60)

−0.93

0.4

0.4

  1. aMean (SD); n (%).
  2. bWelch Two Sample t-test; Pearson’s Chi-squared test.
  3. cFalse discovery rate correction for multiple testing.
  4. The bold values are significant value after the false discovery rate correction for multiple testing.
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