Fig. 3: Receiver operating characteristic (ROC) curves for generalised linear models classifying SA history among individuals with BD, based on beta-values of the six FDR-significant discovery cohort DMPs (“DMPs only”), six clinical correlates of SA history in mood disorder (“Clinical only”), and the beta-values and clinical correlates combined (“DMPs + Clinical combined”).
From: Blood epigenome-wide association studies of suicide attempt in adults with bipolar disorder
AUC of the ROC curves are presented with 95% confidence intervals. A ROC curves are presented for classification of SA history in the discovery cohort (n = 162). B ROC curves are presented for classification of SA history in the replication cohort (n = 95). AUC area under the curve, DMP differentially methylated positions, FDR false discovery rate, SA suicide attempt.
