Fig. 2: Effects of ketamine on EEG vigilance in associaton with serum levels in MDD patients. | Translational Psychiatry

Fig. 2: Effects of ketamine on EEG vigilance in associaton with serum levels in MDD patients.

From: EEG-vigilance regulation is associated with and predicts ketamine response in major depressive disorder

Fig. 2

A Ketamine increases the amount of low vigilance stage B1. Relative to pre-infusion, ketamine increases the amount of stage B1 during end-infusion compared to placebo in all patients with depression, regardless of their clinical outcome. B Association between the changes of stage B1 from infusion to baseline and serum concentration. A positive partial correlation was found between ketamine serum concentration 30 min after the first loading dose and the percentage changes of stage B1 at the second infusion to pre-infusion. Note: *p < 0.05. start-pre, relative changes from the first loading dose (start-infusion) to pre-infusion; end-pre, relative changes from the second infusion (end-infusion) to pre-infusion.

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