Fig. 1: Scatterplots of distribution and concordance status between amyloid PET and plasma Aβ42/40.

Distribution and concordance status of IP-MS-WashU (A) and IA-Elc (B). Plasma Aβ42/40 z-scores and amyloid PET SUVR values of IP-MS-WashU (orange) and IA-Elc (purple) are fitted using spline model (C). Disagreement number (%) between IP-MS-WashU (blue) and IA-Elc (red) were listed according to PET/plasma groups (D). Agreement cases between IP-MS-WashU and IA-Elc are listed in the middle (purple). Abbreviation: Aβ amyloid-β, IA-Elc Elecsys immunoassay from Roche Diagnostics, IP-MS-WashU immunoprecipitation followed by mass spectrometry method developed at Washington, PET positron emission tomography.