Fig. 2: Tau burden according to PET/plasma groups.

Association between tau burden assessed by18F-flortaucipir PET and PET/plasma groups were analyzed using general linear model adjusted for age and sex. Tau deposition in entorhinal, Braak III/IV, and Braak V/VI regions using IP-MS-WashU (A–C) and IA-Elc (D–F). Abbreviation: Aβ amyloid-β, FTP 18F-flortaucipir, IA-Elc Elecsys immunoassay from Roche Diagnostics, IP-MS-WashU immunoprecipitation followed by mass spectrometry method developed at Washington, PET positron emission tomography, SUVR standardized uptake value ratio.