Fig. 3: Psychiatric disorder associated genes identified by EWAS in relation to immune systems.
From: Genetic evidence for causal effects of immune dysfunction in psychiatric disorders: where are we?
A Genes identified by epigenomic wide association studies included in the EWAS Catalog (http://ewascatalog.org/; accessed at January 2023) for attention-deficiency/hyperactive disorder (ADHD), autism spectrum disorder (ASD), depression or depressive symptoms (Dep) and schizophrenia (SCZ) are annotated to genes involved in innate immune response (InnateDB, https://www.innatedb.com/) and ImmPort (https://www.immport.org/). Proportions of reported genes annotated to each immune gene source are shown on y axis. The number of annotated genes and reported genes are shown on the top of each bar. Wordcloud plots for reported genes annotated to ImmPort (C) and InnateDB (B). Text font sizes indicate the number of disorders associated with the gene.
