Table 1 Basic cohort demographic information for both human and rhesus macaque subjects.
From: Extracellular matrix abnormalities in the hippocampus of subjects with substance use disorder
Cohort A: Human subjects for SUD, SUD/MDD, and MDD analyses | ||||
SUD n = 20 | SUD/MDD n = 24 | MDD n = 20 | Control n = 20 | |
Age, years | 34.8 ± 9.0 | 43.9 ± 11.1 | 47 ± 11.4 | 43.2 ± 11.42 |
Sex | ||||
Male | 17 | 16 | 14 | 13 |
Female | 3 | 8 | 6 | 7 |
Race | ||||
White | 13 | 20 | 17 | 11 |
Black | 7 | 4 | 3 | 9 |
Brain pH | 6.57 ± 0.23 | 6.54 ± 0.27 | 6.5 ± 0.32 | 6.5 ± 0.25 |
PMI, Hours | 18.58 ± 8.5 | 20.2 ± 7.6 | 23.7 ± 5.9 | 21.2 ± 6.8 |
Cohort B: PFA fixed samples from control subjects for labeling of synaptic markers and PVB neurons | ||||
Age | 43.0 ± 25.2 | |||
Sex | 2 Male, 1 Female | |||
Hemisphere | 2 Right, 1 Left | |||
Cohort C: Rhesus macaque subjects | ||||
Alcohol drinkers n = 7 | Control n = 5 | |||
Age, years | 7.20 ± 0.04 | 6.90 ± 0.49 | ||
Sex | Male (n = 7) | Male (n = 5) | ||
BAC, mg pct | 101.46±12.76 | NA | ||
