Table 1 Demographic and medical characteristics of the sample.

From: Epigenome-wide association study identifies neonatal DNA methylation associated with two-year attention problems in children born very preterm

Maternal characteristics

Full Sample (N = 617)

Included (N = 393)

Excluded (N = 224)

 

M (SD) or % (n)

M (SD) or % (n)

M (SD) or % (n)

p-value

Minority race or ethnicity

57% (347/606)

52% (205/391)

66% (142/215)

0.002

American Indian/Alaska Native race

0.16% (1/617)

0.25% (1/393)

0% (0/224)

1.00

Asian race

3.7% (23/617)

3.8% (15/393)

3.6% (8/224)

1.00

Native Hawaiian/Other Pacific Islander race

1.3% (8/617)

1% (4/393)

1.8% (4/224)

0.66

Black or African American race

20% (126/617)

21% (81/393)

20% (45/224)

0.96

White race

42% (261/617)

48% (189/393)

32% (72/224)

<0.001

More than one race

22% (136/617)

18% (70/393)

29% (66/224)

<0.001

Unknown/Not reported race

10% (62/617)

8.4% (33/393)

13% (29/224)

0.10

Hispanic/Latino ethnicity

23% (142/617)

21% (83/393)

26% (59/224)

0.17

Ethnicity Unknown

1.3% (8/617)

0% (0/393)

3.6% (8/224)

0.001

Low SES: Hollingshead level 5

9.6% (58/605)

9% (35/391)

11% (23/214)

0.57

Maternal education: < HS/GED

13% (78/604)

15% (57/390)

9.8% (21/214)

0.12

No partner

25% (152/605)

26% (103/391)

23% (49/214)

0.40

Neonatal characteristics

Full Sample (N = 704)

Included (N = 441)

Excluded (N = 263)

 

Multiple gestations

26% (184/697)

28% (123/440)

24% (61/257)

0.26

Vaginal delivery

29% (201/696)

29% (128/440)

29% (73/256)

0.94

Severe retinopathy of prematurity (ROP)

5.9% (41/697)

5.9% (26/440)

5.8% (15/257)

1.00

Necrotizing enterocolitis/sepsis

18% (128/697)

20% (88/440)

16% (40/257)

0.18

Bronchopulmonary dysplasia (BPD)

51% (357/697)

52% (228/440)

50% (129/257)

0.74

Serious brain injury

13% (92/694)

12% (54/439)

15% (38/255)

0.39

Sex = Male

55% (390/704)

54% (238/441)

58% (152/263)

0.36

GA at birth (weeks)

27.01 (1.91)

27.01 (1.93)

27 (1.89)

0.98

Head circumference (cm)

24.46 (2.43)

24.46 (2.46)

24.48 (2.38)

0.91

GA at NICU discharge (weeks)

40.53 (5.43)

40.35 (5.26)

40.85 (5.72)

0.26

Length of NICU stay (days)

94.16 (44.1)

92.8 (42.9)

96.49 (46.2)

0.30

Birth weight (g)

948.3 (281)

948.9 (285)

947.2 (273)

0.94

Weight at discharge (g)

3014 (905)

2990 (856)

3055 (984)

0.38

  1. Note. GA, gestational age; HS, high school; GED, General Equivalency Diploma; SES, socioeconomic status. Minority race or ethnicity was defined as any non-White race (e.g., Black, Asian) or ethnicity (e.g., Hispanic and/or Latino/a). Serious brain injury included parenchymal echodensity, periventricular leukomalacia, or ventricular dilation diagnosed via cranial ultrasound.