Fig. 2: Canonical correlation analysis on POND and HBN cohort data.

A Standardized canonical coefficients for behaviour scores measured from the original (i.e., POND) and replication (i.e., HBN) cohort. Errors bars indicate the standard deviation of canonical coefficients recalculated over 10,000 bootstrap resamples. * denotes |z| > 1.96, where z is the ratio of a coefficient to its standard error. If |z| > 1.96, the coefficient is considered to be stable. B Canonical coefficients for functional connectivity features. * denotes stable coefficients. The top row pertains to the original cohort and the bottom row pertains to the replication cohort. CBCL Child Behaviour Checklist, SCQ Social Communication Questionnaire, TOCS Toronto Obsessive-Compulsive Scale, DAN dorsal attention network, VAN ventral attention network, DMN default mode network, Sal salience network.