Fig. 1: Study design and selection procedure. | Translational Psychiatry

Fig. 1: Study design and selection procedure.

From: Rhesus infant nervous temperament predicts peri-adolescent central amygdala metabolism & behavioral inhibition measured by a machine-learning approach

Fig. 1

a Study design: At 3–4 months old, all candidate animals were evaluated for a range of infant measures during the BBA. Relevant to our study, the BBA yields objective inhibition scores and other temperament ratings for each animal. At 2–3 years old, animals selected for our study were removed from their home colonies, injected with the radiotracer [18F]fludeoxyglucose (FDG), and behaviorally assessed via a 30-minute no-eye-contact (NEC) condition of the human intruder paradigm, after which PET scans were administered to evaluate glucose metabolism during the NEC. b Selection procedure: The selection procedure for our study: 20 of 98 candidate peri-adolescent animals were initially selected based on a stratified sampling of 1 animal from each of 20 bins defined by z scored inhibited temperament scores, assessed during infancy as part of the BBA.

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