Fig. 5: Peri-adolescent Ce metabolism predicts infant BBA measures and concurrent defensive behavior. | Translational Psychiatry

Fig. 5: Peri-adolescent Ce metabolism predicts infant BBA measures and concurrent defensive behavior.

From: Rhesus infant nervous temperament predicts peri-adolescent central amygdala metabolism & behavioral inhibition measured by a machine-learning approach

Fig. 5

a Heatmap of associations between PET-obtained, ROI-defined regional metabolism (y axis) and infant BBA measures (x axis, left) as well as concurrent NEC behaviors as automatically scored by UC Freeze (x axis, right; *p < 0.05). b The association between Ce ROI metabolism and BBA inhibition was not statistically significant (r = 0.32, p = 0.196). c The association between Ce ROI metabolism and total freezing duration during the NEC, however, was significant (r = 0.48, p < 0.05). d The location of the Ce (shown on the Paxinos et al. atlas, left) corresponds to a voxelwise analysis (middle and right) that revealed a significant correlation between NEC freezing behavior and integrated metabolism in a region of the dorsal amygdala encompassing the Ce (p < 0.05, uncorrected). No significant relationships were identified between BST metabolism and infant BBA measures or concurrent defensive behavior (not shown).

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