Table 2 Demographic and clinical information, as well as app data between controls and MDD subjects.

From: Multimodal digital assessment of depression with actigraphy and app in Hong Kong Chinese

 

Controls (N = 47)

MDD (N = 61)

P

Age, mean (SD), y

50.21 (11.88)

50.15 (11.28)

0.92

Female, N (%)

29 (61.7)

42 (68.9)

0.44

17-HDS score, mean (SD)

1.66 (2.04)

8.66 (6.12)

<0.001***

Remission, %

/

51.7

/

Psychomotor retardation, N (%)

/

3 (4.9)

/

Psychomotor agitation, N (%)

/

2 (3.3)

/

HADS-D score, mean (SD)

3.41 (2.97)

8.24 (4.18)

<0.001***

HADS-A score, mean (SD)

4.23 (3.02)

8.44 (4.34)

<0.001***

Marital status, %

  

0.62

 Married/Cohabitating

64.4

59.6

 

 Divorced/Never married/Widowed

35.6

40.4

 

Employment status, yes, %

60

53.6

0.52

Secondary school or above, %

91.1

94.7

0.75

Family income monthly <15,000 HKD, %

11.4

32.7

0.012*

Medication

  

/

 Antidepressants, %

/

72.1

 

 Anxiolytics, %

/

26.2

 

 Antipsychotics, %

/

18.0

 

 Mood stabilizer, %

/

3.3

 

Subjective happiness level

6.63 (1.43)

5.02 (1.70)

<0.001***

Facial expression: AU, mean (SD), %

   

1 (Inner brow raising)

21.02 (5.30)

23.02 (7.88)

0.14

4 (Brow lowering)

21.60 (20.59)

29.70 (20.55)

0.023*

6 (Cheek raising)

25.52 (26.43)

15.51 (21.01)

0.078

12 (Lip corner pulling)

18.21 (17.41)

10.41 (13.21)

0.007**

15 (Lip corner depressing)

17.46 (8.01)

19.45 (9.14)

0.27

Acoustic feature

   

F0 mean (Hz), mean (SD)

   

 Female

169.30 (22.29)

164.12 (24.08)

0.39

 Male

110.33 (14.82)

107.01 (13.63)

0.51

F0 variability (Hz), mean (SD)

   

 Female

51.26 (11.68)

51.19 (10.39)

0.98

 Male

36.88 (13.63)

38.77 (12.42)

0.69

Articulation rate, mean (SD)

4.38 (0.51)

3.97 (0.51)

<0.001***

Pause duration mean, mean (SD)

0.72 (0.21)

0.82 (0.29)

0.10

Pause variability, mean (SD)

0.31 (0.15)

0.41 (0.27)

0.046*

Pause rate, mean (SD)

0.22 (0.085)

0.25 (0.098)

0.13

NLP feature

   

Negative emotion, mean (SD), %

0.26 (0.45)

0.92 (1.10)

<0.001***

Self-reference, mean (SD), %

0.98 (1.11)

1.81 (1.76)

0.018*

  1. 17-HDS 17-item Hamilton depression scale, HADS-D Hospital Anxiety and Depression Scale—Depression subscale, HADS-A Hospital Anxiety and Depression Scale—Anxiety subscale, AU action unit, NLP natural language processing. ***P < 0.001, **P < 0.01, *P < 0.05.