Fig. 2: Generation and characterization of iPSC-derived astrocytes. | Translational Psychiatry

Fig. 2: Generation and characterization of iPSC-derived astrocytes.

From: Molecular mechanisms involved in alcohol craving, IRF3, and endoplasmic reticulum stress: a multi-omics study

Fig. 2

A iPSCs from six AUD patients were generated from peripheral blood mononuclear cells (PBMCs). Those cells all showed normal karyotypes as well as the expression of pluripotency markers. This panel displays representative data for iPSC cells from AUD patients with the three panels showing iPSCs in culture, an example of a normal karyotype, and iPSC-derived astrocytes. B A schematic outline for procedures used in the differentiation of iPSC-derived astrocytes. The panel below the schematic displays representative examples of staining for astrocyte markers (GFAP, CD44 and S100β). MAP1/2 is a marker of neurons.

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