Fig. 5: Correlation of caecal metabolite ethyl 2-(4-oxo-4,5-dihydro-1,3-thiazol-2-yl)acetate with biological and behavioural measures. | Translational Psychiatry

Fig. 5: Correlation of caecal metabolite ethyl 2-(4-oxo-4,5-dihydro-1,3-thiazol-2-yl)acetate with biological and behavioural measures.

From: Exercise mitigates a gut microbiota-mediated reduction in adult hippocampal neurogenesis and associated behaviours in rats

Fig. 5

a Spearman correlation heatmap for caecal ethyl 2-(4-oxo-4,5-dihydro-1,3-thiazol-2-yl)acetate normalised expression, plasma BDNF, IL-6, TNFa, corticosterone, hippocampal BDNF protein levels, number of BrdU+/NeuN+ and DCX+ cells per mm2 in the whole, dorsal, and ventral hippocampus, and microglia soma size in the whole hippocampus. b Spearman correlation heatmap for caecal ethyl 2-(4-oxo-4,5-dihydro-1,3-thiazol-2-yl)acetate normalised expression, performance in the MSLR (large and small separation), NSF, EPM and FST (swimming behaviour); *p < 0.5, **p < 0.01, ***p < 0.001; unadjusted.

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