Table 1 Genome-wide polygenic risk scores for schizophrenia calculated at 5 progressive p thresholds, and their association (beta[p]) with axonal density in association tracts.
CG | iFO | sL | Unc | |
|---|---|---|---|---|
Axonal density | ||||
SZ PRS | ||||
0.1 | −0.008 (0.13) | −0.009 (0.08) | −0.014 (0.008) | 0.001 (0.85) |
0.01 | −0.012 (0.03) | −0.015 (0.006) | −0.018 (0.0007) | −0.006 (0.28) |
0.001 | −0.010 (0.05) | −0.013 (0.01) | −0.015 (0.006) | −0.006 (0.26) |
0.0001 | −0.016 (0.003) | −0.012 (0.02) | −0.016 (0.004) | −0.006 (0.23) |
0.00001 | −0.014 (0.01) | −0.016 (0.003) | −0.017 (0.002) | −0.008 (0.11) |
Orientation dispersion | ||||
SZ PRS | ||||
0.1 | 0.006 (0.26) | 0.009 (0.1) | −0.002 (0.66) | 0.010 (0.06) |
0.01 | 0.014 (0.01) | 0.009 (0.10) | −0.007 (0.21) | 0.008 (0.12) |
0.001 | 0.014 (0.01) | 0.009 (0.08) | −0.001 (0.88) | 0.008 (0.14) |
0.0001 | 0.016 (0.004) | 0.009 (0.08) | −0.006 (0.29) | 0.013 (0.01) |
0.00001 | 0.014 (0.01) | 0.007 (0.22) | 0.003 (0.61) | 0.016 (0.004) |
