Table 3 Association (beta[p]) with axonal density in association tracts of four quasi-independent risk SNP for schizophrenia within the MHC region and of their added risk.

From: Common risk alleles for schizophrenia within the major histocompatibility complex predict white matter microstructure

 

CG

iFO

sL

Unc

Added risk

−0.019 (0.0003)

−0.028 (2*10−6)

−0.027 (7*10−7)

−0.023 (1*10−5)

rs13195636

−0.026 (9*10−7)

−0.030 (2*10−8)

−0.026 (1*10−6)

−0.027 (3*10−7)

rs8192589

−0.018 (0.0008)

−0.030 (2*10−8)

−0.029 (1*10−7)

−0.023 (1*10−5)

rs9461856

−0.009 (0.07)

−0.012 (0.02)

−0.001 (0.84)

−0.013 (0.01)

rs9368789

0.013 (0.01)

0.009 (0.10)

0.013 (0.01)

0.007 (0.22)

  1. Risk variant rs13195636 (A), rs8192589 (G), rs9461856 (G), rs9368789 (C).
  2. CG Cingulum-cingulate gyrus part, iFO Inferior fronto-occipital fasciculus, sL Superior longitudinal fasciculus, Unc Uncinate fasciculus.
  3. Bonferroni corrected (20 tests) significant results are highlighted in bold.
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