Table 1 Direction of differences in cytokines and chemokines between MDD and BD also according to mood episodes.
From: Inflammatory mediators in major depression and bipolar disorder
MDD vs HC | BD vs HC | Euthymia | Depression vs euthymia | Depression vs mania | Mania vs euthymia | |
|---|---|---|---|---|---|---|
CRP | ↑ | ↑ | ↑ | |||
IL-6 | ↑ | ↑ | ↑ | ↓/↑ | ↑ | |
sIL-6 | - | ↑ | ||||
TNF-α | ↑ | ↑ | ↑- | - | - | |
sTNFR2 | ↑ | |||||
sTNRF1 | ↑ | ↑- | ↓ | ↓ | ||
sTNFR80 | ↓ | ↑ | ||||
IL-4 | - | ↑ (Mania) | ↑ | ↓ | ||
IL-10 | ↑ | |||||
CCL2 | ↑ | |||||
CCL3 | - | |||||
CXCL8 (IL-8) | -/↑ | ↓ | ↑ (CSF) | |||
CXCL10 | ↑ | ↑ | ||||
CCL11 | ↑ (Mania) | ↑ |
