Table 3 Determination of changes in neurotrophic factors and oxidative stress parameters before and after Repetitive Transcranial Magnetic Stimulation (rTMS) treatment in patients with major depressive disorder.
Variables | Pre-rTMS (n = 25) | Post-rTMS (n = 26) | p | |
---|---|---|---|---|
BDNF ng/mL | mean ± SD | 3.61 ± 0.86 | 4.49 ± 1.18 | <0.01*a |
S100B ng/L | 194.76 ± 22.91 | 153.84 ± 20.78 | <0.01*a | |
ALLO pg/mL | 691.94 ± 82.18 | 738.60 ± 83.46 | <0.01*a | |
TAS mmol ascorbate Eq./L | 0.71 ± 0.11 | 0.87 ± 0.12 | <0.01*a | |
NT μM | 279.42 ± 76.76 | 351.35 ± 36.87 | <0.01*a | |
DIS μM | 79.88 ± 43.18 | 65.47 ± 40.71 | 0.115a | |
GDNF pg/mL | mean (mşin-max) | 249.92 (154.75–618.91) | 255.36 (247.27–319.61) | <0.01*b |
TOS μmol H2O2 Eq./L | 11.97 (6.8–18.48) | 11.65 (8.81–16) | <0.01*b | |
TT μM | 459.17 (371.24–635.02) | 473.44 (407.85–679.41) | <0.01*b | |
OSI AU | 14.16 (6.58–28.15) | 13.25 (9.49–26.77) | <0.01*b |