Table 1 Participant demographics.
Healthy adults | Depressed Newport adults | Test statistic (vs. healthy) | df | P value | Depressed adults all sites | Test statistic (vs. healthy) | df | P value | |
---|---|---|---|---|---|---|---|---|---|
n | 103 | 169 | 338 | ||||||
Mean age, years, mean ± SD | 39.4 ± 12.8 | 36.5 ± 13.7 | t = 1.76 | 227.4 | 0.079 | 35.8 ± 13.6 | t = 2.48 | 178.65 | 0.014 |
Age range, years | 18–65 | 18–65 | 18–65 | ||||||
Sex, % male | 40.8% | 46.2% | χ2 = 0.55 | 1 | 0.46 | 44.1% | χ2 = 0.23 | 1 | 0.63 |
Ethnicity | |||||||||
Caucasian | 63 | 107 | 233 | ||||||
Asian | 7 | 5 | 19 | ||||||
Hispanic | 7 | 11 | 14 | ||||||
African American | 1 | 2 | 6 | ||||||
Unknown | 25 | 44 | 66 | ||||||
Comorbidities | |||||||||
Any anxiety disorder | 138 (81.7%) | 260 (76.9%) | |||||||
Generalized anxiety disorder | 87 (51.5%) | 117 (34.6%) | |||||||
ADHD | 38 (22.5%) | 43 (12.7%) | |||||||
Bipolar | 0 | 0 | |||||||
OCD | 14 (8.3%) | 38 (10.4%) | |||||||
PTSD | 0 | 0 | |||||||
Current suicidal ideation | 73 (43.2%) | 103 (30.5%) | |||||||
Previous suicide attempt | 10 (5.9%) | 19 (5.6%) | |||||||
Eating disorder | 5 (3.0%) | 11 (3.3%) | |||||||
Personality disorder | 2 (1.2%) | 3 (1.0%) | |||||||
Substance abuse disorder* | 4 (2.4%) | 5 (1.5%) | |||||||
Alcohol-related disorder | 3 (1.8%) | 3 (1.0%) | |||||||
Cannabis-related disorder | 1 (0.6%) | 1 (0.3%) | |||||||
Other substance-related disorder | 1 (0.6%%) | 2 (0.6%) | |||||||
Medications | |||||||||
Any psychotropic | 0 | 69 (40.8%) | 125 (37.0%) | ||||||
SSRI | 0 | 30 (17.8%) | 47 (13.9%) | ||||||
SNRI | 1 (1.0%) | 10 (5.9%) | 19 (5.6%) | ||||||
Antipsychotics | 0 | 4 (2.4%) | 18 (5.3%) | ||||||
Stimulants | 0 | 2 (1.2%) | 8 (2.4%) | ||||||
Benzodiazepines | 1 (1.0%) | 16 (9.5%) | 31 (9.2%) | ||||||
Anticonvulsants | 0 | 5 (3.0%) | 9 (2.7%) | ||||||
Anticonvulsant mood stabilizers | 0 | 5 (3.0%) | 10 (3.0%) | ||||||
Lithium | 0 | 1 (0.6%) | 3 (0.89%) | ||||||
Atypical antidepressants | 0 | 17 (10.1%) | 26 (7.7%) |