Table 1 Participant demographics.

From: A multi-site 99mTc-HMPAO SPECT study of cerebral blood flow in a community sample of patients with major depression

 

Healthy adults

Depressed Newport adults

Test statistic (vs. healthy)

df

P value

Depressed adults all sites

Test statistic (vs. healthy)

df

P value

n

103

169

   

338

   

Mean age, years, mean ± SD

39.4 ± 12.8

36.5 ± 13.7

t = 1.76

227.4

0.079

35.8 ± 13.6

t = 2.48

178.65

0.014

Age range, years

18–65

18–65

   

18–65

   

Sex, % male

40.8%

46.2%

χ2 = 0.55

1

0.46

44.1%

χ2 = 0.23

1

0.63

Ethnicity

Caucasian

63

107

   

233

   

Asian

7

5

   

19

   

Hispanic

7

11

   

14

   

African American

1

2

   

6

   

Unknown

25

44

   

66

   

Comorbidities

Any anxiety disorder

 

138 (81.7%)

   

260 (76.9%)

   

Generalized anxiety disorder

 

87 (51.5%)

   

117 (34.6%)

   

ADHD

 

38 (22.5%)

   

43 (12.7%)

   

Bipolar

 

0

   

0

   

OCD

 

14 (8.3%)

   

38 (10.4%)

   

PTSD

 

0

   

0

   

Current suicidal ideation

 

73 (43.2%)

   

103 (30.5%)

   

Previous suicide attempt

 

10 (5.9%)

   

19 (5.6%)

   

Eating disorder

 

5 (3.0%)

   

11 (3.3%)

   

Personality disorder

 

2 (1.2%)

   

3 (1.0%)

   

Substance abuse disorder*

 

4 (2.4%)

   

5 (1.5%)

   

Alcohol-related disorder

 

3 (1.8%)

   

3 (1.0%)

   

Cannabis-related disorder

 

1 (0.6%)

   

1 (0.3%)

   

Other substance-related disorder

 

1 (0.6%%)

   

2 (0.6%)

   

Medications

Any psychotropic

0

69 (40.8%)

   

125 (37.0%)

   

SSRI

0

30 (17.8%)

   

47 (13.9%)

   

SNRI

1 (1.0%)

10 (5.9%)

   

19 (5.6%)

   

Antipsychotics

0

4 (2.4%)

   

18 (5.3%)

   

Stimulants

0

2 (1.2%)

   

8 (2.4%)

   

Benzodiazepines

1 (1.0%)

16 (9.5%)

   

31 (9.2%)

   

Anticonvulsants

0

5 (3.0%)

   

9 (2.7%)

   

Anticonvulsant mood stabilizers

0

5 (3.0%)

   

10 (3.0%)

   

Lithium

0

1 (0.6%)

   

3 (0.89%)

   

Atypical antidepressants

0

17 (10.1%)

   

26 (7.7%)

   
  1. Newport:
  2. • Resting scans were not acquired in 22 patients with depression and 26 healthy controls.
  3. • CPT scans were not acquired in 2 patients with depression and 1 healthy control.
  4. • 1 healthy control was missing demographic information.
  5. All sites:
  6. • Resting scans were not acquired in 36 patients with depression and 26 healthy controls.
  7. • CPT scans were not acquired in 2 patients with depression and 1 healthy control.
  8. • 1 healthy control was missing demographic information.
  9. *1 patient had both alcohol and cannabis-related disorder.