Fig. 3: Cytochrome c oxidase (CIV) activity and mitochondrion-specific respiration in the PFC and AMY from POL-exposed and control male and female adult offspring.
From: Prenatal immune activation in mice induces long-term alterations in brain mitochondrial function
a Cytochrome c oxidase activity (CIV, pmol O2 /(s*mg ww)) in the PFC of male and female adult offspring. POL-exposed mice offspring show higher CIV activity. Multiple comparisons: **P = 0.0052. b Mitochondrion-specific respiration for NP, NSP, NSE, and SE in the PFC of male offspring. Multiple comparisons: **P = 0.003. c Mitochondrion-specific respiration for NP, NSP, NSE, and SE in the PFC of female offspring. d Cytochrome c oxidase activity (CIV, pmol O2/(s*mg ww)) in the AMY of male and female adult offspring. Multiple comparisons: *P < 0.05, **P = 0.0036. e Mitochondrion-specific respiration for NP, NSP, NSE, and SE in the AMY of male offspring. Multiple comparisons: *P = 0.05. f Mitochondrion-specific respiration for NP, NSP, NSE, and SE in the AMY of female offspring. Multiple comparisons: *P ≤ 0.05. Bar plots with individual values represent means ± SD. n = 7 per sex from 7 litter per group.
