Table 1 Demographic data and clinical measures among three groups.

From: The mediating effect of the amygdala-frontal circuit on the association between depressive symptoms and cognitive function in Alzheimer’s disease

Groups

ADD

ADND

HC

F-value

p-value

Subjects

60

60

60

-

-

Age

71.18 ± 7.75

71.93 ± 6.84

71.72 ± 4.20

0.21

0.82

Sex (F/M)

40/20

36/24

38/22

5.73

0.75

Education

12.23 ± 3.12

12.02 ± 2.63

12.30 ± 2.94

0.16

0.87

MMSE

18.58 ± 4.06

18.60 ± 3.71

28.30 ± 1.22

149.10

<0.001b,c

GDS-30

13.15 ± 3.37

1.98 ± 1.64

1.60 ± 1.39

445.19

<0.001a,c

CDR

0.68 ± 0.24

0.69 ± 0.25

0

197.96

<0.001b,c

  1. ADD Alzheimer’s disease patients with depressive symptoms, ADND Alzheimer’s disease patients without depressive symptoms, HC healthy controls, MMSE Mini-Mental State Examination, GDS-30 the Geriatric Depression Screening Scale with 30 items, CDR Clinical Dementia Rating Scale.
  2. a–c: post-hoc analysis following one-way analysis of variance (a: ADD vs. ADND, b: ADND vs. HC, and c: ADD vs. HC).
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