Table 2 Brain regions with significant differences in amygdala-based FC among ADD, ADND, and HC groups.

Seed region	Area	L/R	Voxels	MNI X Y Z			F/T-value
Seed region	Area	L/R	Voxels	X	Y	Z	F/T-value
Left amygdala
ANOVA	MCC	L/R	1553	−12	−24	33	26.20
	STG	L	329	−51	−30	3	19.71
		R	292	54	−18	9	18.27
	IFG	L	178	−36	27	−21	14.87
	SMA	R	239	6	−9	63	14.06
	PHG	R	207	30	−21	−18	13.13
ADD < ADND	IFG	L	125	−48	27	−9	−4.58
ADD < HC	MCC	L/R	1525	9	−18	33	−6.51
	SMA	R	225	6	−9	63	−6.35
	STG	L	326	−51	−30	3	−6.71
		R	291	51	3	0	−5.94
	PHG	R	201	30	−21	−18	−5.80
	IFG	L	150	−36	27	−21	−6.46
ADND < HC	MCC	L/R	932	−12	24	33	−6.39
	STG	R	192	54	−21	9	−5.70
		L	52	−60	−9	3	−3.98
Right amygdala
ANOVA	MCC	L/R	587	−9	−36	24	23.01
	IFG	L	129	−30	21	−21	20.15
	PHG	R	139	18	−12	−15	17.23
		L	194	−27	−9	−30	16.68
	STG	L	136	−54	−9	−3	16.64
		R	205	54	−18	9	16.09
ADD < ADND	IFG	L	42	−51	33	−9	−4.67
ADD < HC	MCC	L/R	584	12	−15	33	−5.99
	STG	L	135	−54	−9	−3	−5.92
		R	200	63	−21	0	−4.73
	PHG	L	194	−27	−12	−27	−6.17
		R	137	36	−18	−24	−5.65
	IFG	L	125	−30	21	−24	−6.94
ADND < HC	MCC	L/R	586	−9	−36	24	−6.72
	STG	R	159	54	−18	9	−5.57
	PHG	L	53	−33	−18	−33	−4.91
		R	66	36	−18	−36	−4.63

ADD AD patients with depressive symptoms, ADND AD patients without depressive symptoms, HC healthy control, IFG inferior frontal gyrus, MCC median cingulate and paracingulate gyrus, STG superior temporal gyrus, SMA supplementary motor area, PHG parahippocampal gyrus.

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