Table 2 Change of adiposity markers during follow-up by any antidepressant use prior to baseline and during follow-up.
From: Long-term changes in adiposity markers during and after antidepressant therapy in a community cohort
Change in adiposity markers during follow-up | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Crude change | Model 1 | Model 2 | Model 3 | ||||||
Mean (SD) | βa | (95%CI) | β | (95%CI) | β | (95%CI) | β | (95%CI) | |
Body Mass Index [kg/m2] (n = 2462) | |||||||||
Antidepressants prior to baseline | |||||||||
Number of compounds | — | −0.01 | (−0.07, 0.04) | −0.08* | (−0.14, −0.02) | −0.12*** | (−0.18, −0.06) | −0.12*** | (−0.19, −0.05) |
Antidepressants during follow-up | |||||||||
Any antidepressants | 0.9 (2.2) | 0.35*** | (0.19, 0.50) | 0.42*** | (0.25, 0.59) | 0.34*** | (0.16, 0.52) | 0.32*** | (0.13, 0.50) |
No antidepressants (ref.) | 0.6 (1.7) | 0 (ref.) | — | 0 (ref.) | — | 0 (ref.) | — | 0 (ref.) | — |
Waist circumference [cm] (n = 2475) | |||||||||
Antidepressants prior to baseline | |||||||||
Number of compounds | — | 0.06 | (−0.19, 0.30) | −0.19 | (−0.46, 0.08) | −0.28 | (−0.56, 0.00) | −0.28* | (−0.56, −0.01) |
Antidepressants during follow-up | |||||||||
Any antidepressants | 4.6 (7.3) | 1.39*** | (0.73, 2.05) | 1.52*** | (0.79, 2.25) | 1.29** | (0.52, 2.06) | 1.23** | (0.44, 2.01) |
No antidepressants (ref.) | 3.2 (6.6) | 0 (ref.) | — | 0 (ref.) | — | 0 (ref.) | — | 0 (ref.) | — |
Fat mass [%] (n = 2079) | |||||||||
Antidepressants prior to baseline | |||||||||
Number of compounds | — | −0.01 | (−0.18, 0.17) | −0.04 | (−0.23, 0.15) | −0.11 | (−0.30, 0.09) | −0.09 | (−0.29, 0.11) |
Antidepressants during follow-up | |||||||||
Any antidepressants | 2.5 (5.8) | 0.37 | (−0.10, 0.84) | 0.39 | (−0.13, 0.91) | 0.30 | (−0.25, 0.84) | 0.18 | (−0.38, 0.75) |
No antidepressants (ref.) | 2.1 (5.7) | 0 (ref.) | — | 0 (ref.) | — | 0 (ref.) | — | 0 (ref.) | — |
