Fig. 2: Association between changes in cortical thickness and opioid craving. | Translational Psychiatry

Fig. 2: Association between changes in cortical thickness and opioid craving.

From: Medial prefrontal neuroplasticity during extended-release naltrexone treatment of opioid use disorder – a longitudinal structural magnetic resonance imaging study

Fig. 2

a Significant correlation between the change in opioid craving and the change in cortical thickness from pre-treatment to on-treatment in the OUD group revealed by whole-brain regression, thresholded at corrected p < 0.05. b Association between the change in opioid craving and the change in cortical thickness of the mPFC/aCC region of interest. OUD opioid use disorder, mPFC medial prefrontal cortex, aCC anterior cingulate cortex. Reduction = pre-treatment minus on-treatment. The shaded area represents 95% confidence interval.

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