Fig. 3: Mapping of MOR binding potential to cortical thickness change.

a Curvilinear association between MOR binding potential and the change in cortical thickness (pre-treatment minus on-treatment) across cortical regions in the OUD group. b MOR receptor binding potential map obtained from a large sample (N = 204) [¹¹C]carfentanil positron emission tomographic imaging study (Kantonen et al. [38], NeuroImage). c Unthresholded map of cortical thickness change (pre-treatment minus on-treatment) in the OUD group. OUD opioid use disorder, MOR μ-opioid receptor.