Fig. 4: Differences in brain region-specific longitudinal WPE changes and their correlation with symptoms.

A Group differences in ROI level WPE between the SZ0W group and the SZ12W group were accessed by paired-sample t test. Significant difference (Bonferroni corrected, 4 comparisons) was found only in left ventral caudate. B Two groups WPE for the four ROIs (**PBonf < 0.01). C Correlations between the reduction rate of the subscores and the total score of the PANSS scale (y axis) and WPE of the right ventral caudate before treatment (x axis) in SZ12W group (Bonferroni corrected, 4 comparisons).