Fig. 1: Serum cytokine and inflammatory proteins in iHUD versus HC. | Translational Psychiatry

Fig. 1: Serum cytokine and inflammatory proteins in iHUD versus HC.

From: Serum cytokines and inflammatory proteins in individuals with heroin use disorder: potential mechanistically based biomarkers for diagnosis

Fig. 1

A Box and whisker plot for all the 29 targets that showed significant differences between iHUD and HC groups. Targets are organized by canonical cytokine families (19 targets; chemokines, interleukin-related, growth factors, and TNF-related), and the remainder as “other targets”. The box marks 25-75 percentiles; the midline marks the median and the whiskers mark 5-95 percentiles. p-values are shown for group comparisons per target, after FDR correction: *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001. B Re-plotting of panel A data as the difference in mean values in iHUD and HC (i.e., mean of iHUD - mean of HC). Positive values indicate that the target has levels iHUD>HC, and negative values indicate levels iHUD < HC. Full data for statistical comparisons are in the Supplementary Material.

Back to article page