Fig. 2: Principal component analysis (PCA) for the 19 cytokines (representing 4 cytokine families in Fig. 1: chemokines, interleukin-related, growth factors, and TNF-related).

A Scree plot, showing the proportion of variance accounted for by consecutive principal components (PC). B Scatter plot for individual scores for PC1 and PC2. C Comparison of PC1 scores between iHUD (n = 21) and HC (n = 24). D Receiver-operating characteristic (ROC) curve for PC1 scores as a measure to detect HUD vs HC as binary diagnostic outcomes.