Table 2 Demographic information of the Stanley Medical Research Institute Brain Bank cohort (USA).

From: Defective regulation of the eIF2-eIF2B translational axis underlies depressive-like behavior in mice and correlates with major depressive disorder in humans

 

HC

MDD

Statistics (test performed)

Sample size

10

19a

-

Sex (F/M)

3/7

9/10

p = 0.36 (X2 test)

Age (mean years)

46.40 ± 11.57

42.89 ± 11.90

p = 0.45 (Unpaired t test)

Race

9 W / 1H

18 W / 1H

p = 0.63 (X2 test)

Duration of Illness (years)

-

12.50 ± 7.82

-

PMI (mean hours)

23.50 ± 10.77

29.95 ± 12.23

p = 0.17 (Unpaired t test)

Suicide (%)

0

73.6b

-

Antidepressant use (%)

0

73.6

-

Antipyschotic use (%)

0

31.6

-

  1. Values represent mean ± Standard Deviation.
  2. F Female, M Male, W White, H Hispanic, PMI post mortem interval (hours), HC healthy control, MDD major depressive disorder.
  3. acombining individuals diagnosed with MDD with or without psychotic features.
  4. b81.8% of the individuals diagnosed as MDD with psychotic features (11 patients) had suicide as cause of death.
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