Table 4 Linear regression model for MADRS score.

From: Circadian clock dysregulation: a potential mechanism of depression in obstructive sleep apnea patients

MADRS score

Model

R2 = 0.543, F = 31.256, p < 0.001

Parameter

B

B 95% CI

t

p value

Constant

−6.603

−11.935–(−1.272)

−2.465

0.016

ISI score

0.750

0.490–1.009

5.744

<0.001

AM score of CQ

0.416

0.114–0.717

2.744

0.007

morning PER1 gene expression

4.310

0.165–8.456

2.069

0.042

  1. Excluded variables: ME score of CQ, ESS score, AHI in nREM, Desaturation Index, morning BMAL1 gene expression, morning CLOCK gene expression, morning CRY1 gene expression, morning NPAS2 gene expression, morning NR1D1 gene expression.
  2. AM subjective amplitude, BMAL1 brain and muscle ARNT-like 1, CLOCK circadian locomotor output cycles kaput, CRY1 cryptochrome 1, CQ Chronotype Questionnaire, ISI Insomnia Severity Index, MADRS Montgomery-Åsberg Depression Rating Scale, NPAS2 neuronal PAS domain 2, NR1D1 nuclear receptor subfamily 1 group D member 1, PER1 period 1.
  3. Bold values in the tables mark statistically significant data.
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